Lay Waste is very strong at farming minions and harassing enemy champions.
Ask your allies to help point out when you should use Requiem to get kills in different lanes.
Try to fight Sylas when he isn't able to take your ultimate.
Sylas's healthbar can be deceptive, watch out for his Kingslayer!
The stats shown here show some valuable Karthus versus Sylas counter stats that may help us distinguish the differences between this pair of champs. Karthus’s KDA ratio ([kills + assists] / deaths) of NaN is more than Sylas’s ratio of NaN, demonstrating that Karthus may be more central to his team's team fighting capability than Sylas..
Karthus normally has a slightly smaller longest killing spree than his counter does. Commonly, he receives less damage than Sylas. This is usually reflective of different amounts of tankyness, yet it can also illustrate that the champion with increased health has less mobility and thus is unable to escape further damage when poked or engaged.
Both League of Legends champions are great. Both have their pros and cons. In League's current meta, Karthus usually loses when taking on Sylas, with a 48.2% win rate. Thus, Karthus makes a poor counter to Sylas.
While Karthus does have a lower win rate compared to Sylas, when on opposite teams, Karthus also has a greater difficulty level that makes him a more difficult character to pick up and master. You should be careful when picking Karthus into Sylasas his relative depth means that you may not be able to reach his full potential without a significant amount of practice beforehand.
Moreover, Karthus also has some amount of CC and other utility, a similar amount to Sylas. This often makes her just as valuable during teamfights, especially when trying to counter champions with a lot of burst damage.
While there isn't one best champion in League of Legends, in Karthus vs Sylas matchups, Sylas is the better champion with a lower win rate, more champion depth, and a similar amount of utility to help out your allies during team fights.
Karthus is a somewhat poor counter to Sylas. Make sure you focus your gameplay on increasing your gold and cs and destroying objectives. If you are able to do that, you should be able to stand on your own as Karthus against Sylas.
If you would like to learn all of the intricacies of Karthus to counter Sylas during both the early game and mid / late game phases of League of Legends, you should keep reading to pick up a few extra lessons on this matchup. If you listen to the build and tips displayed here, you should grow your win rate significantly and be that much closer to League of Legends pro players.
Karthus most often picks up a similar amount of CS relative to Sylas. Champs who on average don't take many minion kills often don't require much CS to be effective, such as support champions. They are able to scale well off of their skills, stats, and first items alone. Yet, champs with a lot of CS, such as hyper-carries, typically need a lot of items to be effective. In either situation, try to surpass the numbers reported here to do well.
The top items to focus on in your Karthus versus Sylas build include Rabadon's Deathcap, Malignance, and Stormsurge. When Karthus used at least these three pieces in his build, he performed much better vs. Sylas than with many other common counter builds. In fact, Karthus boasted an average win rate of 48.2% when playing against Sylas with this counter build.
To have the greatest probability of crushing Sylas as Karthus, Karthus players should use the Dark Harvest, Cheap Shot, Eyeball Collection, Ultimate Hunter, Presence of Mind, and Last Stand runes from the Domination and Precision rune sets. Out of all the runes we have analyed for Karthus vs Sylas counters, this composite of runes yielded the highest win rate. Moreover, these runes gave a 48.2% win rate overall.
By default, tips, stats, and builds on how to beat Sylas as Karthus are given for all ranked divisions. To filter the stats and builds to an individual rank, you can use the selection menu located earlier in the counter matchup guide.