Lay Waste is very strong at farming minions and harassing enemy champions.
Ask your allies to help point out when you should use Requiem to get kills in different lanes.
Keep your distance to avoid being Flung back into Singed's allies.
Singed needs to run close to your team to be effective. Try to take advantage of this by using crowd control effects on him while attacking his allies.
Be careful when chasing Singed. He's very difficult to bring down, and can leave his Poison Trail to damage you in your pursuit.
The stats shown on this page clarify several important Karthus versus Singed matchup stats that may help us understand the distinctions between this pair of champions. Karthus’s KDA ratio ([kills + assists] / deaths) of NaN is more than Singed’s ratio of NaN, highlighting that Karthus may be more central to his team's team fighting effectiveness than Singed..
Karthus normally has a slightly larger longest killing spree than his opponent does. Commonly, he takes less damage than Singed. This typically indicates differing health capacities, yet it can also indicate that the champion with more HP has less agility and thus is not able to kite away from additional damage when engaged or poked.
Both LoL champions are great. Both have their strengths, weaknesses, and counters. In League's current meta, Karthus usually loses when facing off against Singed, with a 48.7% win rate. Thus, Karthus makes a poor counter for Singed.
While Karthus does have a lower winrate compared to Singed, when they face off with one another, Karthus also has a greater learning curve that makes him a more challenging character to learn. You should be careful when picking Karthus into Singedas his relative depth means you may not be able to reach his full potential without a significant amount of practice beforehand.
Moreover, Karthus also has some amount of utility and CC, a similar amount to Singed. This often makes her just as valuable during team fights, especially when facing champions with a lot of burst damage.
While there isn't one best champion for every situation in League of Legends, in Karthus vs Singed matchups, Singed is the better champ with a lower win rate, more champion depth, and a similar amount of utility to help out your allied champions during teamfights.
Karthus is a somewhat poor counter to Singed. You will do well by focussing your tactics on increasing your gold income and clearing objectives. If you are able to do that, you should be able to stand on your own as Karthus against Singed.
To truly master Karthus to counter Singed during both the laning and mid / late game phases of League of Legends, you should keep reading to pick up a few extra tips and tricks for this matchup. If you pay attention to the build and tips presented above, you should grow your win rate by a lot and be closer to League of Legends pro players.
Karthus most often racks up less CS relative to Singed. Champions who on average don't acquire many minion kills often don't require much CS to be effective, such as sup champs. They are capable of scaling well off of their skills, stats, and first items alone. Yet, champs with large amounts of CS, such as hyper-carries, typically require many items to be effective. In either situation, try to do better than the values displayed on this page to do well.
The most crucial items to focus on in your Karthus versus Singed build include Rabadon's Deathcap, Void Staff, and Liandry's Torment. When Karthus bought at least these three items in his build, he did significantly better against Singed than with many other commonly used builds. In fact, Karthus had an average winrate of 48.7% battling Singed with this counter build.
To have the best likelihood of vanquishing Singed as Karthus, Karthus players should take the First Strike, Magical Footwear, Future's Market, Cosmic Insight, Eyeball Collection, and Ultimate Hunter runes from the Inspiration and Domination rune sets. Out of all the runes we have analyed for Karthus vs Singed LoL games, this set of runes yielded the best win rate. Notably, these runes provided a 48.7% win rate overall.
If you need to see Karthus vs Singed tips and counter builds for a an individual division, feel free to select one from the selection menu shown above. At first, the statistics and guides displayed are computed using every round finished with these champs.