Lay Waste is very strong at farming minions and harassing enemy champions.
Ask your allies to help point out when you should use Requiem to get kills in different lanes.
Be ready to dodge Shen's taunt and punish him if he misses.
Once Shen reaches level 6, watch out for his global-range ultimate, which can turn fights quickly.
The stats shown here emphasize several critical Karthus against Shen matchup statistics that may help us realize the distinctions between the two. For instance, Karthus’s KDA ratio ([kills + assists] / deaths) of NaN is more than Shen’s ratio of NaN, indicating that Karthus may be more central to his team's team fighting capability than Shen. This observation is largely fueled by the differences in deaths.
Karthus typically has a slightly larger longest kill spree than his enemy does. On average, he receives less damage than Shen. This typically indicates differing health capacities, yet it can also imply that the champion with higher health has less mobility and thus is not able to escape further damage when poked or engaged.
Both League of Legends champions are great champions. Both champs have their pros and cons. In League's current meta, Karthus usually loses when playing against Shen, with a 46.8% win rate. Therefore, Karthus makes a bad counter for Shen.
While Karthus does have a lower win rate compared to Shen, when on opposite teams, Karthus also has a much greater difficulty level that makes him a more difficult champion to learn. You may get destroyed when picking Karthus into Shenas his relative depth means you may not be able to reach his full potential without a lot of practice beforehand.
Furthermore, Karthus has some amount of CC and other utility, a similar amount to Shen. This often makes her just as valuable during teamfights, especially when facing champions with a lot of burst damage.
While there is not a single best champion for every situation in League of Legends, in Karthus vs Shen matchups, Shen is the better champion with a much lower win rate, more champion depth, and a similar amount of utility to help out your team members during team fights.
Karthus is a terribly counter to Shen. You will do well by focussing your tactics on keeping up your CS and taking out objectives. If you do that, you should be able to stand on your own as Karthus against Shen.
If you would like to learn all of the intricacies of Karthus to counter Shen during both the early game and mid / late game phases of League of Legends, you should keep reading to learn a few extra tricks and insights into this matchup. If you listen to the build and suggestions shown here, you will increase your win rate by a lot and be that much closer to League of Legends pro players.
Karthus on average picks up less CS relative to Shen. Champions who on average don't acquire many minion kills often don't have to have much CS to be effective, such as sup champs. These kinds of champions are able to scale properly off of their skills, stats, and first items alone. Yet, champs with large amounts of CS, such as hyper-carries, usually need several high cost items to be effective. In either situation, try to do better than the values displayed on this page to do well.
The best items to focus on in your Karthus versus Shen build include Rabadon's Deathcap, Shadowflame, and Liandry's Torment. When Karthus included at least these three items in his build, he did a lot better countering Shen than with most other common item sets. In fact, Karthus boasted an average win rate of 46.8% when countering Shen with these items in his kit.
To have the best chance of annihilating Shen as Karthus, Karthus players should equip the Dark Harvest, Cheap Shot, Eyeball Collection, Ultimate Hunter, Gathering Storm, and Transcendence runes from the Domination and Sorcery rune sets. Of all the runes players chose for Karthus vs Shen counter picks, this sequence of runes yielded the best win rate. Moreover, these runes provided a 46.8% winrate overall.
If you need to view Karthus versus Shen tips and matchup stats and build suggestions for a a distinct player tier, feel free to choose one from the selection menu provided above. By default, the stats and guides shown are calculated using every game played with these champs.