Lay Waste is very strong at farming minions and harassing enemy champions.
Ask your allies to help point out when you should use Requiem to get kills in different lanes.
After being marked, move away from Quinn so she can't take advantage of it.
Keep tabs on Quinn's position. Behind Enemy Lines can enable Valor to cross the map very quickly and attack you by surprise.
When Quinn is using Behind Enemy Lines, damaging her removes her Move Speed bonus temporarily.
The stat comparisons shown on this page underscore some strategic Karthus against Quinn counter statistics that may help us distinguish the distinctions between the two. For instance, Karthus’s KDA ratio ([kills + assists] / deaths) of NaN is better than Quinn’s KDA ratio of NaN, highlighting that Karthus may be more central to his team's team fighting potential than Quinn..
Karthus normally has a similar longest killing spree as his opponent does. Typically, he receives more damage than Quinn. This typically indicates different amounts of tankyness, yet it can also hint that the one champ has less mobility and thus is not able to kite away from further harm when poked or engaged.
Both LoL champions are great. Both champs have their strengths, weaknesses, and counters. In League's current meta, Karthus usually loses when playing against Quinn, with a 48.8% win rate. As a result, Karthus makes a poor counter to Quinn.
While Karthus does have a lower win rate compared to Quinn, when they face off with one another, Karthus also has a greater level of difficulty that makes him a more difficult character to develop with. You still need to be cautious when picking Karthus into Quinnas his relative depth means you may not be able to unleash his full potential without a lot of practice beforehand.
Moreover, Karthus has some amount of CC and other utility, a similar amount to Quinn. This makes her just as valuable during team fights, especially when trying to counter champions with a lot of burst damage.
While there isn't one best champion overall in League of Legends, in Karthus vs Quinn matchups, Quinn is the better champion with a lower win rate, more champion depth, and a similar amount of utility to help out your allied champions during late stage team fights.
Karthus is a somewhat poor counter to Quinn. You will do well by focussing your play on maximizing your gold and cs and destroying objectives. If you can do that, you should hold your own as Karthus against Quinn.
If you would like to truly master Karthus in order to counter Quinn during both the laning and mid / late game phases of League of Legends, you should continue reading to pick up a few extra tricks and insights into this matchup. If you listen to the build and tips displayed here, you should increase your win rate by a lot and be that much closer to League of Legends pro players.
Karthus typically racks up less CS as Quinn. Champions who typically don't acquire much CS typically don't need much CS to be valuable teammates, such as sup champs. They are capable of scaling well off of their skills, stats, and first items alone. Yet, champs with large amounts of CS, such as hyper-carries, often have to have several high cost items to be effective. In either situation, try to surpass the values reported on this page to do well.
The best items to have in your Karthus versus Quinn build consist of Malignance, Stormsurge, and Liandry's Torment. When Karthus incorporated at least these three items in his build, he performed significantly better against Quinn than with most other typical item sets. In fact, Karthus boasted an average winrate of 48.8% when countering Quinn with these items in his kit.
To have the best probability of defeating Quinn as Karthus, Karthus players should use the Dark Harvest, Cheap Shot, Eyeball Collection, Ultimate Hunter, Gathering Storm, and Transcendence runes from the Domination and Sorcery rune sets. Of all the rune combinations players picked for Karthus vs Quinn fights, this mix of runes resulted in the highest win rate. In fact, these runes gave a 48.8% winrate overall.
By default, tips, stats, and builds on how to beat Quinn as Karthus are displayed for all ranked divisions combined. If you would like to filter the stats and builds to a particular division, you may use the selection menu located earlier in the counter matchup guide.