Lay Waste is very strong at farming minions and harassing enemy champions.
Ask your allies to help point out when you should use Requiem to get kills in different lanes.
The stat comparisons shown on this page show several strategic Karthus versus Qiyana matchup stats that may help you understand the differences and similarities between the pair. Karthus’s KDA ratio ([kills + assists] / deaths) of NaN is greater than Qiyana’s KDA ratio of NaN, highlighting that Karthus may be more central to his team's team fighting capability than Qiyana..
Karthus usually has a similar longest killing spree as his counter does. On average, he receives more damage than Qiyana. This commonly reflects different amounts of tankyness, but it can also hint that the one champion has less agility and thus is unable to escape further damage when engaged or poked.
Both League of Legends champions are great. Both have their strengths, weaknesses, and counters. In the game's current meta, Karthus usually wins when playing against Qiyana, with a 51.4% win rate. Thus, Karthus makes a good counter for Qiyana.
While Karthus does have a higher winrate than Qiyana, when facing one another, Karthus also has a lower level of difficulty that makes him a less complex champion to develop with. You should be careful when picking Karthus into Qiyanaas his relative depth means that you may not be able to unleash his full potential without a lot of practice beforehand.
Additionally, Karthus has some amount of CC and other utility, a similar amount to Qiyana. This often makes her just as valuable during teamfights, especially when fighting champions with a lot of burst damage.
While there isn't one best champion in League of Legends, in Karthus vs Qiyana matchups, Karthus is the better champ with a higher win rate, less champion complexity, and a similar amount of utility to help out your allied champions during team fights.
Karthus is a decent counter for Qiyana. Make sure you focus your gameplay on increasing your gold and cs and taking out objectives. If you do that, you should be able to stand on your own as Karthus against Qiyana.
If you would like to learn all of the intricacies of Karthus in order to counter Qiyana during both the laning and mid / late game phases of League of Legends, you should continue reading to pick up a few extra lessons on this matchup. If you mind the build and suggestions displayed here, you will increase your win rate by a lot and be closer to League of Legends pro players.
Karthus often picks up less CS as Qiyana. Champions who typically don't take many minion kills often don't need much CS to be valuable teammates, such as support champions. These kinds of champions are capable of scaling well off of their skills, stats, and first items alone. Yet, champs with a lot of CS, such as hyper-carries, often need a lot of items to be effective. In either situation, try to do better than the values displayed here to do well.
The best items to focus on in your Karthus versus Qiyana build consist of Rabadon's Deathcap, Malignance, and Liandry's Torment. When Karthus used at least these three pieces in his build, he performed significantly better vs Qiyana than with many other commonly used counter builds. In fact, Karthus had an average win rate of 51.4% when countering Qiyana with this build.
To have the greatest likelihood of crushing Qiyana as Karthus, you should equip the First Strike, Magical Footwear, Future's Market, Cosmic Insight, Eyeball Collection, and Ultimate Hunter runes from the Inspiration and Domination rune sets. Of all the runes players chose for Karthus vs Qiyana clashes, this composite of runes yielded the greatest win rate. Moreover, these runes averaged a 51.4% win rate overall.
By default, tips, stats, and builds on how to beat Qiyana as Karthus are given for all ranked divisions. If you would like to filter the stats and builds to a particular division, you should use the selection menu earlier in the counter matchup guide.