Lay Waste is very strong at farming minions and harassing enemy champions.
Ask your allies to help point out when you should use Requiem to get kills in different lanes.
Pantheon's Aegis Assault makes him invulnerable from the front. Get behind him or wait it out.
Grand Starfall gives several seconds of warning before Pantheon arrives. Use this time to get out of the way or to form a plan to deal with him.
Be careful near Pantheon if your health is low - a thrown Comet Spear executes low health enemies.
The stats provided here show some valuable Karthus vs. Pantheon counter statistics that may help you appreciate the differences and similarities between these two champs. As an example, Karthus’s KDA ratio ([kills + assists] / deaths) of NaN is more than Pantheon’s ratio of NaN, indicating that Karthus may be more central to his team's team fighting effectiveness than Pantheon..
Karthus usually has a similar longest kill spree as his counter does. Typically, he receives a similar amount of damage to Pantheon. This is usually reflective of differing health capacities, yet it can also show that the champion with higher health has less agility and thus is unable to flee from additional damage when poked or engaged.
Both League of Legends champions are great champions. Both have their pros and cons. In the game's current meta, Karthus usually loses when playing against Pantheon, with a 48.6% win rate. As a result, Karthus makes a poor counter to Pantheon.
While Karthus does have a lower win rate compared to Pantheon, when on opposite teams, Karthus also has a much greater level of difficulty that makes him a more time consuming character to develop with. You should be careful when picking Karthus into Pantheonas his relative depth means that you may not be able to reach his full potential without a lot of practice beforehand.
Moreover, Karthus has some amount of utility and CC, a similar amount to Pantheon. This makes her just as valuable during team fights, especially when facing champions with a ton of burst damage.
While there is not a single best champion in League of Legends, in Karthus vs Pantheon matchups, Pantheon is the better champion with a lower win rate, more champion depth, and a similar amount of utility to help out your team members during teamfights.
Karthus is a somewhat poor counter to Pantheon. You will do well by focussing your tactics on increasing your gold income and clearing objectives. If you can do that, you should do very well as Karthus against Pantheon.
If you would like to truly master Karthus in order to counter Pantheon during both the lane and mid / late game phases of League of Legends, you should keep reading to learn a few extra tricks and insights into this matchup. If you pay attention to the build and tips displayed above, you will increase your win rate by a lot and be that much closer to League of Legends pro players.
Karthus on average accumulates a similar amount of CS relative to Pantheon. Champions who typically don't acquire many minion kills typically don't require much CS to be effective, such as support champions. They are able to scale well off of their abilities and first items alone. Yet, champions with large amounts of CS, such as hyper-carries, typically have to have a lot of items to be effective. In either situation, try to surpass the values reported on this page to do well.
The ideal items to have in your Karthus versus Pantheon build include Void Staff, Shadowflame, and Liandry's Torment. When Karthus incorporated at least these three items in his build, he did significantly better vs Pantheon than with many other typical counter builds. In fact, Karthus had an average winrate of 48.6% when countering Pantheon with these items in his kit.
To have the greatest chance of defeating Pantheon as Karthus, you should equip the Dark Harvest, Cheap Shot, Eyeball Collection, Ultimate Hunter, Presence of Mind, and Last Stand runes from the Domination and Precision rune sets. Of all the rune builds we have analyed for Karthus vs Pantheon counters, this combo of runes yielded the best win rate. Moreover, these runes averaged a 48.6% winrate overall.
If you would like to get Karthus vs Pantheon tips and counter stats for a a distinct division rank, feel free to select one from the selection menu displayed above. By default, the stats and strategies given are calculated using every round run with both champs.