Lay Waste is very strong at farming minions and harassing enemy champions.
Ask your allies to help point out when you should use Requiem to get kills in different lanes.
Stay spread out to minimize the impact of Lee Sin's ultimate, Dragon's Rage.
Lee Sin relies heavily on following up with his abilities. Use disables to prevent him from chaining together his abilities and attacks.
Lee Sin has powerful tools to combat physical damage in Iron Will and Cripple but he is still vulnerable to magic damage.
The stat comparisons shown here highlight several critical Karthus vs. K'Sante matchup stats that may help you explain the distinctions between the two. Karthus’s KDA ratio ([kills + assists] / deaths) of NaN is greater than K'Sante’s ratio of NaN, highlighting that Karthus may be more central to his team's team fighting capability than K'Sante..
Karthus typically has a slightly larger longest killing spree than his enemy does. Commonly, he takes less damage than K'Sante. This typically indicates different amounts of tankyness, yet it can also hint that the one champion has less mobility and thus is unable to kite away from further damage when engaged or poked.
Both LoL champs are great champions. Both champs have their strengths, weaknesses, and counters. In League's current meta, Karthus usually fairs equally well when taking on K'Sante, with a 49.4% win rate. Thus, Karthus makes an ok counter for K'Sante.
While Karthus does have a lower winrate compared to K'Sante, when they face off with one another, Karthus also has a lower difficulty level that makes him a less time consuming character to learn. You still need to be cautious when picking Karthus into K'Santeas his relative depth means you may not be able to reach his full potential without a lot of practice beforehand.
Moreover, Karthus has some amount of utility and CC, a similar amount to K'Sante. This often makes her just as valuable during team fights, especially when trying to counter champions with a lot of burst damage.
While there isn't a single best champion in League of Legends, in Karthus vs K'Sante matchups, K'Sante is the better champion with a similar win rate, less champion complexity, and a similar amount of utility to help out your allies during teamfights.
Karthus is a somewhat poor counter for K'Sante. Focus your tactics on keeping up your CS and taking out objectives. If you are able to do that, you should hold your own as Karthus against K'Sante.
If you would like to learn all of the intricacies of Karthus in order to counter K'Sante during both the early game and mid / late game phases of League of Legends, you should keep reading to gather a few extra tips and tricks for this matchup. If you pay attention to the build and stats presented above, you should grow your win rate by a lot and be that much closer to League of Legends pro players.
Karthus often picks up less CS compared to K'Sante. Champions who typically don't take many minion kills often don't need much CS to be valuable teammates, such as sup champs. They are capable of scaling properly off of their abilities and first items alone. Yet, champs with large amounts of CS, such as hyper-carries, typically have to have several high cost items to be effective. In either case, try to surpass the numbers shown here to do well.
The top items to have in your Karthus versus K'Sante build include Malignance, Stormsurge, and Liandry's Torment. When Karthus used at least these three items in his build, he performed much better against K'Sante than with many other commonly used builds. In fact, Karthus boasted an average winrate of 49.4% battling K'Sante with this counter build.
To have the best chance of beating K'Sante as Karthus, Karthus players should equip the First Strike, Magical Footwear, Future's Market, Cosmic Insight, Eyeball Collection, and Ultimate Hunter runes from the Inspiration and Domination rune sets. Out of all the rune sets we have analyed for Karthus vs K'Sante battles, this order of runes resulted in the highest win rate. Moreover, these runes gave a 49.4% winrate overall.
By default, tips, statistics, and builds on how to beat K'Sante as Karthus are given for all ranked divisions combined. If you would like to scope the statistics and builds to an individual player tier, you may use the selection menu located earlier in the counter matchup guide.