Lay Waste is very strong at farming minions and harassing enemy champions.
Ask your allies to help point out when you should use Requiem to get kills in different lanes.
Taste Their Fear deals bonus damage to targets that are isolated. Gain an advantage by fighting near allied minions, champions, or turrets.
Leap and Void Assault have long cooldowns. Kha'Zix is very vulnerable when these are not available.
The stats shown on this page emphasize several strategic Karthus against Kha'Zix matchup stats that may help you realize the differences and similarities between the two. For instance, Karthus’s KDA ratio ([kills + assists] / deaths) of NaN is greater than Kha'Zix’s ratio of NaN, indicating that Karthus may be more central to his team's team fighting capacity than Kha'Zix..
Karthus often has a slightly smaller longest kill spree than his matchup does. On average, he receives less damage than Kha'Zix. This is usually reflective of differing health capacities, yet it can also indicate that the one champion has less mobility and thus is unable to kite away from additional damage when engaged or poked.
Both LoL champions are great champions. Both have their strengths, weaknesses, and counters. In League's current meta, Karthus usually loses when facing off against Kha'Zix, with a 48.0% win rate. Therefore, Karthus makes a poor counter to Kha'Zix.
While Karthus does have a lower win rate than Kha'Zix, when facing one another, Karthus also has a greater level of difficulty that makes him a more time consuming champion to develop with. You should expect to face a difficult match when picking Karthus into Kha'Zixas his relative depth means that you may not be able to unleash his full potential without a lot of practice beforehand.
Furthermore, Karthus also has some amount of utility and CC, a similar amount to Kha'Zix. This makes her just as valuable during teamfights, especially when fighting champions with a lot of burst damage.
While there isn't a single best champion overall in League of Legends, in Karthus vs Kha'Zix matchups, Kha'Zix is the better champion with a lower win rate, more champion depth, and a similar amount of utility to help out your allied champions during team fights.
Karthus is a garbage counter to Kha'Zix. You will do well by focussing your tactics on keeping up your CS and destroying objectives. If you can do that, you should do very well as Karthus against Kha'Zix.
To learn all of the intricacies of Karthus to counter Kha'Zix during both the early game and mid / late game phases of League of Legends, you should continue reading to pick up a few extra tips and tricks for this matchup. If you mind the build and suggestions displayed here, you will grow your win rate by a lot and be that much closer to League of Legends pro players.
Karthus usually picks up much more CS relative to Kha'Zix. Champs who typically don't get many minion kills often don't need much CS to be effective, such as supports. These kinds of champions are capable of scaling well off of their skills, stats, and first items alone. Yet, champions with large amounts of CS, such as hyper-carries, usually require many items to be effective. In either situation, try to exceed the numbers reported on this page to do well.
The most crucial items to focus on in your Karthus versus Kha'Zix build include Malignance, Void Staff, and Shadowflame. When Karthus used at least these three items in his build, he did significantly better against Kha'Zix than with most other typical builds. In fact, Karthus boasted an average winrate of 48.0% when playing against Kha'Zix with this counter build.
To have the best chance of beating Kha'Zix as Karthus, you should equip the Dark Harvest, Cheap Shot, Eyeball Collection, Ultimate Hunter, Gathering Storm, and Transcendence runes from the Domination and Sorcery rune sets. Out of all the rune sets that we analyzed for Karthus vs Kha'Zix matchups, this mixture of runes yielded the greatest win rate. Moreover, these runes averaged a 48.0% win rate overall.
By default, tips, stats, and builds on how to beat Kha'Zix as Karthus are displayed for all ranked divisions. If you want to scope the statistics and builds to an individual player tier, you can use the selection menu located earlier on the page.