Lay Waste is very strong at farming minions and harassing enemy champions.
Ask your allies to help point out when you should use Requiem to get kills in different lanes.
Kayle starts the game as a weaker melee champion. Try to put her behind before she ascends to her ranged form.
Kayle is usually a fragile target. If you see her ultimate cast on an ally, switch to attacking her.
Divine Judgment only grants Kayle or her allies immunity to damage. Slows and stuns can still be applied, so trap them if they're being overzealous.
The stat comparisons shown on this page underscore some influential Karthus vs. Kayle matchup statistics that can help us appreciate the differences and similarities between the pair. For instance, Karthus’s KDA ratio ([kills + assists] / deaths) of NaN is better than Kayle’s KDA ratio of NaN, demonstrating that Karthus may be more central to his team's team fighting capability than Kayle..
Karthus often has a slightly larger longest kill spree than his opponent does. Typically, he receives more damage than Kayle. This often reflects different amounts of tankyness; however, it can also indicate that the one champion has less mobility and thus is unable to kite away from further damage when poked or engaged.
Both League champions are great. Both have their pros and cons. In the game's current meta, Karthus usually loses when facing off against Kayle, with a 46.4% win rate. Thus, Karthus makes a poor counter for Kayle.
While Karthus does have a lower win rate compared to Kayle, when facing one another, Karthus also has a greater level of difficulty that makes him a more difficult character to develop with. You should be very concerned when picking Karthus into Kayleas his relative depth means that you may not be able to reach his full potential without a significant amount of practice beforehand.
Moreover, Karthus also has some amount of CC and other utility, a similar amount to Kayle. This makes her just as valuable during teamfights, especially when fighting champions with a ton of burst damage.
While there is not a single best champion in League of Legends, in Karthus vs Kayle matchups, Kayle is the better champ with a much lower win rate, similar champion depth, and a similar amount of utility to help out your teammates during late stage team fights.
Karthus is a bad counter to Kayle. Make sure you focus your strategy on keeping up your gold income and destroying objectives. If you are able to do that, you should be able to stand on your own as Karthus against Kayle.
To truly master Karthus in order to counter Kayle during both the laning and mid / late game phases of League of Legends, you should continue reading to learn a few extra tips and tricks for this matchup. If you pay attention to the build and tips shown above, you will increase your win rate by a lot and be closer to League of Legends pro players.
Karthus usually accumulates less CS compared to Kayle. Champs who on average don't get many minion kills typically don't have to have much CS to be valuable teammates, such as supports. They are capable of scaling well off of their skills, stats, and first items alone. Yet, champions with large amounts of CS, such as hyper-carries, typically need many items to be effective. In either situation, try to surpass the values reported on this page to do well.
The most crucial items to use in your Karthus versus Kayle build consist of Rabadon's Deathcap, Malignance, and Stormsurge. When Karthus incorporated at least these three pieces in his build, he did significantly better when fighting Kayle than with many other typical builds. In fact, Karthus boasted an average win rate of 46.4% when playing against Kayle with these items in his kit.
To have the best likelihood of beating Kayle as Karthus, Karthus players should take the Dark Harvest, Cheap Shot, Eyeball Collection, Ultimate Hunter, Gathering Storm, and Transcendence runes from the Domination and Sorcery rune sets. Out of all the rune builds players picked for Karthus vs Kayle counter picks, this mixture of runes yielded the greatest win rate. Notably, these runes provided a 46.4% win rate overall.
If you need to get Karthus versus Kayle tips and counter builds for a a specific rank, feel free to choose one from the selection menu displayed above. If viewing for the first time, the statistics and strategies given are calculated using every round run with these champions.