Lay Waste is very strong at farming minions and harassing enemy champions.
Ask your allies to help point out when you should use Requiem to get kills in different lanes.
It takes 6 spell casts for Kassadin's slow, Force Pulse, to become castable. If he levels up that ability, judiciously use your own skills while laning against him.
Kassadin deals mostly magic damage. If he's doing well consider buying magic resist items like Mercury's Treads and Banshee's Veil.
Each time Kassadin consecutively uses Riftwalk, he pays more and more mana. Keep this in mind as you chase him.
The stat comparisons shown on this page clarify several influential Karthus versus Kassadin matchup statistics that may help you understand the differences and similarities between the pair. For instance, Karthus’s KDA ratio ([kills + assists] / deaths) of NaN is more than Kassadin’s KDA ratio of NaN, indicating that Karthus may be more central to his team's team fighting capability than Kassadin..
Karthus often has a slightly smaller longest kill spree than his enemy does. Commonly, he takes less damage than Kassadin. This is usually reflective of different amounts of tankyness; however, it can also show that the one champ has less mobility and thus is not able to escape further harm when engaged or poked.
Both LoL champs are great. Both have their pros and cons. In League's current meta, Karthus usually loses when facing off against Kassadin, with a 48.2% win rate. As a result, Karthus makes a poor counter for Kassadin.
While Karthus does have a lower winrate than Kassadin, when they face off with one another, Karthus also has a lower difficulty level that makes him a less challenging champion to pick up and master. You should be careful when picking Karthus into Kassadinas his relative depth means that you may not be able to reach his full potential without a lot of practice beforehand.
Additionally, Karthus also has some amount of utility and CC, a similar amount to Kassadin. This often makes her just as valuable during teamfights, especially when facing champions with a ton of burst damage.
While there isn't one best champion for every situation in League of Legends, in Karthus vs Kassadin matchups, Kassadin is the better champ with a lower win rate, less champion complexity, and a similar amount of utility to help out your teammates during team fights.
Karthus is a somewhat poor counter for Kassadin. Focus your actions on increasing your gold and cs and clearing objectives. If you can do that, you should hold your own as Karthus against Kassadin.
If you would like to truly master Karthus to counter Kassadin during both the lane and mid / late game phases of League of Legends, you should continue reading to gather a few extra tips and tricks for this matchup. If you listen to the build and tips shown here, you should grow your win rate significantly and be that much closer to League of Legends pro players.
Karthus most often picks up less CS relative to Kassadin. Champs who typically don't take much CS often don't need much CS to be valuable teammates, such as support champions. These kinds of champions are capable of scaling well off of their skills, stats, and first items alone. Yet, champions with a lot of CS, such as hyper-carries, usually need many items to be effective. In either case, try to surpass the values shown on this page to do well.
The best items to focus on in your Karthus versus Kassadin build include Malignance, Shadowflame, and Stormsurge. When Karthus included at least these three pieces in his build, he performed much better versus Kassadin than with most other common counter builds. In fact, Karthus boasted an average winrate of 48.2% battling Kassadin with this counter build.
To have the highest chance of crushing Kassadin as Karthus, Karthus players should take the First Strike, Magical Footwear, Future's Market, Cosmic Insight, Eyeball Collection, and Ultimate Hunter runes from the Inspiration and Domination rune sets. Out of all the rune sets that we analyzed for Karthus vs Kassadin face-offs, this blending of runes resulted in the highest win rate. Notably, these runes gave a 48.2% winrate overall.
If you want to view Karthus vs Kassadin tips and matchup stats and build suggestions for a a specific division, feel free to select one from the selection menu above. If viewing for the first time, the statistics and build suggestions given are computed using all rounds completed with these champions.