Lay Waste is very strong at farming minions and harassing enemy champions.
Ask your allies to help point out when you should use Requiem to get kills in different lanes.
Janna's at her strongest when buffing another ally. If you can harass her ally, it will weaken her ability to fight you.
Save an interrupt ability for when Janna uses her ultimate.
Listen for the charge up sound on Howling Gale in case Janna is trying to hit you with it from off screen or from brush.
The stats shown on this page highlight several important Karthus versus Janna counter stats that can help us appreciate the differences between the two. Karthus’s KDA ratio ([kills + assists] / deaths) of NaN is better than Janna’s KDA ratio of NaN, indicating that Karthus may be more central to his team's team fighting capability than Janna. This observation is largely a result of the differences in killsdeaths.
Karthus often has a much larger longest killing spree than his counter does. Typically, he receives more damage than Janna. This is usually reflective of differing health capacities, yet it can also hint that the champion with higher HP has less mobility and thus is not able to flee from additional harm when poked or engaged.
Both League champs are great champions. Both have their strengths, weaknesses, and counters. In the game's current meta, Karthus usually loses when trying to fight Janna, with a 42.2% win rate. Therefore, Karthus makes a poor counter to Janna.
While Karthus does have a much lower win rate compared to Janna, when they face off with one another, Karthus also has a greater learning curve that makes him a more difficult champ to learn. You should be very concerned when picking Karthus into Jannaas his relative depth means that you may not be able to unleash his full potential without a lot of practice beforehand.
Furthermore, Karthus has some amount of CC and other utility, a similar amount to Janna. This makes her just as valuable during team fights, especially when trying to counter champions with a ton of burst damage.
While there isn't a single best champion in League of Legends, in Karthus vs Janna matchups, Janna is the better champ with a much lower win rate, similar champion depth, and a similar amount of utility to help out your teammates during team fights.
Karthus is a trash counter for Janna. Focus your actions on increasing your CS and clearing objectives. If you can do that, you should hold your own as Karthus against Janna.
If you would like to learn all of the intricacies of Karthus in order to counter Janna during both the early game and mid / late game phases of League of Legends, you should continue reading to gather a few extra tricks and insights into this matchup. If you pay attention to the build and tips presented above, you will increase your win rate significantly and be that much closer to League of Legends pro players.
Karthus usually accumulates much more CS as Janna. Champs who typically don't acquire many minion kills typically don't require much CS to be valuable teammates, such as supports. They are capable of scaling well off of their abilities and first items alone. Yet, champs with a lot of CS, such as hyper-carries, often require a lot of items to be effective. In either case, try to surpass the numbers shown on this page to do well.
The most important items to focus on in your Karthus versus Janna build include Malignance, Stormsurge, and Liandry's Torment. When Karthus combined at least these three items in his build, he performed significantly better versus Janna than with most other typical item sets. In fact, Karthus had an average win rate of 42.2% battling Janna with this counter build.
To have the best likelihood of vanquishing Janna as Karthus, Karthus players should equip the Dark Harvest, Cheap Shot, Eyeball Collection, Ultimate Hunter, Presence of Mind, and Last Stand runes from the Domination and Precision rune sets. Of all the rune combinations players used for Karthus vs Janna clashes, this blending of runes yielded the greatest win rate. In fact, these runes averaged a 42.2% win rate overall.
By default, tips, stats, and builds on how to beat Janna as Karthus are shown for all ranked divisions. To scope the statistics and builds to a distinct division, you should use the selection menu located earlier on the page.