Lay Waste is very strong at farming minions and harassing enemy champions.
Ask your allies to help point out when you should use Requiem to get kills in different lanes.
Try to gank Anivia when she's laning. With multiple people, it is easier to ensure that her egg dies.
If you're playing a ranged champion, stay far enough away from Anivia so you can dodge Flash Frost more easily.
Try to fight Anivia in the lanes. In the jungle she can block pathways with lower ranks of Crystallize.
The stat comparisons shown on this page clarify some strategic Karthus against Anivia counter statistics that can help you distinguish the distinctions between this set of champions. As an example, Karthus’s KDA ratio ([kills + assists] / deaths) of NaN is better than Anivia’s ratio of NaN, indicating that Karthus may be more central to his team's team fighting potential than Anivia. This observation is in large part fueled by the differences in deaths.
Karthus usually has a similar longest killing spree as his counter does. Commonly, he receives a similar amount of damage to Anivia. This often reflects differing health capacities; however, it can also illustrate that the one champ has less mobility and thus is not able to escape further harm when engaged or poked.
Both League champions are great champions. Both champs have their strengths, weaknesses, and counters. In League's current meta, Karthus usually loses when playing against Anivia, with a 45.8% win rate. Thus, Karthus makes a bad counter for Anivia.
While Karthus does have a much lower winrate compared to Anivia, when facing one another, Karthus also has a lower difficulty level that makes him a less challenging character to develop with. You should expect to face a difficult match when picking Karthus into Aniviaas his relative depth means you may not be able to unleash his full potential without a lot of practice beforehand.
Moreover, Karthus also has some amount of CC and other utility, a similar amount to Anivia. This makes her just as valuable during teamfights, especially when trying to counter champions with a ton of burst damage.
While there isn't a single best champion overall in League of Legends, in Karthus vs Anivia matchups, Anivia is the better champion with a much lower win rate, less champion complexity, and a similar amount of utility to help out your teammates during late stage team fights.
Karthus is a trash counter for Anivia. Make sure you focus your tactics on keeping up your gold and cs and taking out objectives. If you do that, you should do very well as Karthus against Anivia.
To learn all of the intricacies of Karthus in order to counter Anivia during both the lane and mid / late game phases of League of Legends, you should continue reading to pick up a few extra tricks and insights into this matchup. If you pay attention to the build and suggestions shown here, you will grow your win rate by a lot and be that much closer to League of Legends pro players.
Karthus on average accumulates less CS compared to Anivia. Champions who on average don't earn many minion kills often don't require much CS to be effective, such as sup champs. They are able to scale properly off of their abilities and first items alone. Yet, champions with a lot of CS, such as hyper-carries, usually have to have several high cost items to be effective. In either situation, try to surpass the values displayed here to do well.
The most crucial items to use in your Karthus versus Anivia build include Malignance, Void Staff, and Liandry's Torment. When Karthus used at least these three items in his build, he did much better versus Anivia than with most other commonly used builds. In fact, Karthus had an average winrate of 45.8% battling Anivia with this build.
To have the best likelihood of annihilating Anivia as Karthus, Karthus players should equip the Dark Harvest, Cheap Shot, Eyeball Collection, Ultimate Hunter, Gathering Storm, and Transcendence runes from the Domination and Sorcery rune sets. Of all the runes players picked for Karthus vs Anivia matchups, this combo of runes resulted in the highest win rate. Moreover, these runes gave a 45.8% winrate overall.
By default, tips, statistics, and builds on how to beat Anivia as Karthus are displayed for all skill levels combined. To narrow the stats and builds to an individual division, you may use the selection menu located earlier in the counter matchup guide.