Don't be too conservative with Mantra. Gathering Fire is strongest in teamfights, making it easy to recharge Mantra multiple times.
Gathering Fire rewards aggressive play. Look to land abilities and basic attacks on your opponent to lower Mantra's cooldown and stay on the offensive.
When using Focused Resolve, slow your opponents with Inner Flame or speed yourself up with Inspire if you're having trouble sticking to a target.
Deny Vayne the opportunity to pin you against walls.
Vayne is fragile - turn the pressure up on her and she will be forced to play cautiously.
The stat comparisons shown here feature some strategic Karma versus Vayne counter statistics that can help us realize the differences between this pair of champs. As an example, Karma’s KDA ratio ([kills + assists] / deaths) of NaN is more than Vayne’s KDA ratio of NaN, showing that Karma may be more central to her team's team fighting capability than Vayne. This observation is in large part caused by the differences in assists.
Karma usually has a significantly smaller longest killing spree than her counter does. Commonly, she takes less damage than Vayne. This often reflects different amounts of tankyness, but it can also show that the one champ has less agility and thus is unable to kite away from additional harm when engaged or poked.
Both LoL champs are great champions. Both have their strengths, weaknesses, and counters. In League's current meta, Karma usually loses when playing against Vayne, with a 47.3% win rate. Therefore, Karma makes a bad counter to Vayne.
While Karma does have a lower winrate than Vayne, when they face off with one another, Karma also has a lower learning curve that makes her a less time consuming character to learn. You should be very concerned when picking Karma into Vayne.
Furthermore, Karma has a good amount of CC and other utility, a similar amount to Vayne. This often makes her just as valuable during teamfights, especially when trying to counter champions with a ton of burst damage.
While there isn't a single best champion for every situation in League of Legends, in Karma vs Vayne matchups, Vayne is the better champ with a lower win rate, less champion complexity, and a similar amount of utility to help out your allied champions during teamfights.
Karma is a garbage counter to Vayne. Focus your gameplay on maximizing your gold income and taking out objectives. If you are able to do that, you should be able to stand on your own as Karma against Vayne.
If you would like to truly master Karma to counter Vayne during both the laning and mid / late game phases of League of Legends, you should keep reading to learn a few extra tricks and insights into this matchup. If you listen to the build and tips displayed here, you will grow your win rate significantly and be that much closer to League of Legends pro players.
Karma on average racks up less CS relative to Vayne. Champions who typically don't take much CS typically don't have to have much CS to be valuable teammates, such as support champions. They are capable of scaling properly off of their abilities and first items alone. Yet, champions with large amounts of CS, such as hyper-carries, typically have to have a lot of items to be effective. In either case, try to exceed the numbers reported on this page to do well.
The top items to focus on in your Karma versus Vayne build include Shurelya's Battlesong, Dream Maker, and Imperial Mandate. When Karma included at least these three pieces in her build, she performed a lot better against Vayne than with most other common builds. In fact, Karma had an average winrate of 47.3% battling Vayne with this counter build.
To have the best chance of annihilating Vayne as Karma, you should use the Summon Aery, Manaflow Band, Transcendence, Scorch, Biscuit Delivery, and Cosmic Insight runes from the Sorcery and Inspiration rune sets. Of all the runes players picked for Karma vs Vayne counterpicks, this composite of runes resulted in the highest win rate. In fact, these runes provided a 47.3% winrate overall.
If you would like to get Karma versus Vayne tips and builds for a a specific division rank, please choose one from the selection menu above. At first, the stats and strategies shown are calculated using all matches with data with both champs.