Don't be too conservative with Mantra. Gathering Fire is strongest in teamfights, making it easy to recharge Mantra multiple times.
Gathering Fire rewards aggressive play. Look to land abilities and basic attacks on your opponent to lower Mantra's cooldown and stay on the offensive.
When using Focused Resolve, slow your opponents with Inner Flame or speed yourself up with Inspire if you're having trouble sticking to a target.
Karthus can cast spells for a short duration after he is killed. Move away from his corpse to be safe.
Make sure you always have enough health to survive Requiem, even if you have to go back to the base more frequently to heal.
The stats shown here emphasize several strategic Karma against Karthus counter statistics that may help us grasp the distinctions between the two. For instance, Karma’s KDA ratio ([kills + assists] / deaths) of NaN is greater than Karthus’s ratio of NaN, demonstrating that Karma may be more central to her team's team fighting potential than Karthus..
Karma normally has a significantly smaller longest kill spree than her counter does. Commonly, she takes less damage than Karthus. This often reflects different amounts of tankyness; however, it can also show that the one champion has less agility and thus is unable to kite away from additional damage when poked or engaged.
Both League champions are great. Both have their pros and cons. In the game's current meta, Karma usually fairs equally well when playing against Karthus, with a 50.7% win rate. Therefore, Karma makes an ok counter for Karthus.
While Karma does have a higher winrate compared to Karthus, when on opposite teams, Karma also has a lower level of difficulty that makes her a less difficult character to develop with. You still need to be cautious when picking Karma into Karthus.
Moreover, Karma also has a good amount of utility and CC, a similar amount to Karthus. This often makes her just as valuable during team fights, especially when trying to counter champions with a ton of burst damage.
While there isn't one best champion for every situation in League of Legends, in Karma vs Karthus matchups, Karma is the better champ with a similar win rate, less champion complexity, and a similar amount of utility to help out your allies during teamfights.
Karma is a decent counter for Karthus. Make sure you focus your tactics on maximizing your gold income and destroying objectives. If you can do that, you should do very well as Karma against Karthus.
If you would like to truly master Karma to counter Karthus during both the lane and mid / late game phases of League of Legends, you should keep reading to gather a few extra tips and tricks for this matchup. If you pay attention to the build and stats shown above, you will increase your win rate significantly and be closer to League of Legends pro players.
Karma most often picks up a similar amount of CS relative to Karthus. Champs who typically don't get much CS usualy don't have to have much CS to be valuable teammates, such as supports. They are capable of scaling properly off of their abilities and first items alone. Yet, champions with large amounts of CS, such as hyper-carries, often require a lot of items to be effective. In either situation, try to do better than the numbers shown on this page to do well.
The top items to prioritize in your Karma versus Karthus build include Zaz'Zak's Realmspike, Imperial Mandate, and Staff of Flowing Water. When Karma used at least these three pieces in her build, she did much better vs. Karthus than with many other commonly used builds. In fact, Karma boasted an average win rate of 50.7% battling Karthus with this counter build.
To have the greatest probability of crushing Karthus as Karma, you should equip the Arcane Comet, Manaflow Band, Transcendence, Scorch, Biscuit Delivery, and Cosmic Insight runes from the Sorcery and Inspiration rune sets. Of all the rune builds players chose for Karma vs Karthus battles, this order of runes yielded the greatest win rate. Moreover, these runes provided a 50.7% winrate overall.
By default, tips, stats, and builds on how to beat Karthus as Karma are displayed for all skill levels, merged. If you want to narrow the statistics and builds to a specific division, you can use the selection menu located earlier in the counter matchup guide.