Make sure to buy items that will evolve at least 1 or 2 of your spells.
Work with your teammates to set up your Ultimate and optimize damage with your passive.
Try to catch enemy carries alone to burst them with Icathian Rain.
Spell Shields won't block the damage from Deadly Venom, but they will block the effects Twitch can trigger with it.
If you suspect Twitch has left the lane, let your teammates know that Twitch is ''MIA.''
Twitch is fragile. Work with teammates to focus on him when you're able to catch him out of Camouflage.
The stat comparisons provided here emphasize several significant Kai'Sa against Twitch matchup stats that can help us realize the differences between the pair. For instance, Kai'Sa’s KDA ratio ([kills + assists] / deaths) of NaN is more than Twitch’s KDA ratio of NaN, demonstrating that Kai'Sa may be more central to her team's team fighting capacity than Twitch..
Kai'Sa often has a similar longest killing spree as her foe does. On average, she receives a similar amount of damage to Twitch. This often reflects different amounts of tankyness, yet it can also hint that the champ with higher HP has less agility and thus is not able to kite away from additional harm when poked or engaged.
Both League of Legends champs are great. Both champs have their pros and cons. In the game's current meta, Kai'Sa usually loses when facing off against Twitch, with a 47.2% win rate. As a result, Kai'Sa makes a poor counter for Twitch.
While Kai'Sa does have a lower winrate compared to Twitch, when facing one another, Kai'Sa also has a greater level of difficulty that makes her a more challenging champ to learn. You should expect to face a difficult match when picking Kai'Sa into Twitch.
Furthermore, Kai'Sa has only a small amount of utility and CC, a similar amount to Twitch. This often makes her just as valuable during team fights, especially when facing champions with a ton of burst damage.
While there is not a single best champion for every situation in League of Legends, in Kai'Sa vs Twitch matchups, Twitch is the better champion with a lower win rate, similar champion depth, and a similar amount of utility to help out your teammates during late stage team fights.
Kai'Sa is a terribly counter for Twitch. You will do well by focussing your gameplay on keeping up your CS and destroying objectives. If you are able to do that, you should be able to stand on your own as Kai'Sa against Twitch.
If you would like to truly master Kai'Sa to counter Twitch during both the lane and mid / late game phases of League of Legends, you should keep reading to pick up a few extra tricks and insights into this matchup. If you listen to the build and stats presented above, you should grow your win rate significantly and be that much closer to League of Legends pro players.
Kai'Sa usually accumulates a similar amount of CS compared to Twitch. Champs who typically don't take many minion kills often don't need much CS to be valuable teammates, such as sup champs. These kinds of champions are able to scale well off of their skills, stats, and first items alone. Yet, champions with a lot of CS, such as hyper-carries, typically have to have a lot of items to be effective. In either case, try to exceed the values reported here to do well.
The ideal items to focus on in your Kai'Sa versus Twitch build include Bloodthirster, Kraken Slayer, and Navori Quickblades. When Kai'Sa bought at least these three pieces in her build, she did a lot better vs Twitch than with many other commonly used builds. In fact, Kai'Sa had an average win rate of 47.2% battling Twitch with this counter build.
To have the greatest chance of annihilating Twitch as Kai'Sa, Kai'Sa players should use the Lethal Tempo, Presence of Mind, Legend: Bloodline, Coup de Grace, Magical Footwear, and Biscuit Delivery runes from the Precision and Inspiration rune sets. Of all the rune sets players used for Kai'Sa vs Twitch counterpicks, this combination of runes yielded the greatest win rate. In fact, these runes gave a 47.2% winrate overall.
If you want to view Kai'Sa vs Twitch tips and builds for a a specific division, feel free to select one from the selection menu provided above. By default, the statistics and build suggestions displayed are computed using all games completed with both champions.