Make sure to buy items that will evolve at least 1 or 2 of your spells.
Work with your teammates to set up your Ultimate and optimize damage with your passive.
Try to catch enemy carries alone to burst them with Icathian Rain.
It takes 6 spell casts for Kassadin's slow, Force Pulse, to become castable. If he levels up that ability, judiciously use your own skills while laning against him.
Kassadin deals mostly magic damage. If he's doing well consider buying magic resist items like Mercury's Treads and Banshee's Veil.
Each time Kassadin consecutively uses Riftwalk, he pays more and more mana. Keep this in mind as you chase him.
The stat comparisons shown here highlight several vital Kai'Sa against Kassadin matchup statistics that may help you explain the differences between the two. As an example, Kai'Sa’s KDA ratio ([kills + assists] / deaths) of NaN is better than Kassadin’s ratio of NaN, showing that Kai'Sa may be more central to her team's team fighting capability than Kassadin..
Kai'Sa often has a similar longest killing spree as her counter does. Commonly, she receives less damage than Kassadin. This typically indicates differing health capacities, but it can also illustrate that the champion with higher health has less agility and thus is not able to kite away from further harm when poked or engaged.
Both League champs are great champions. Both have their pros and cons. In League's current meta, Kai'Sa usually loses when playing against Kassadin, with a 46.2% win rate. Therefore, Kai'Sa makes a poor counter for Kassadin.
While Kai'Sa does have a lower winrate compared to Kassadin, when they face off with one another, Kai'Sa also has a lower difficulty level that makes her a less difficult character to learn. You should expect to face a difficult match when picking Kai'Sa into Kassadin.
Additionally, Kai'Sa also has only a small amount of CC and other utility, a similar amount to Kassadin. This makes her just as valuable during team fights, especially when facing champions with a lot of burst damage.
While there isn't one best champion in League of Legends, in Kai'Sa vs Kassadin matchups, Kassadin is the better champion with a much lower win rate, less champion complexity, and a similar amount of utility to help out your team members during teamfights.
Kai'Sa is a garbage counter to Kassadin. Focus your tactics on keeping up your CS and clearing objectives. If you are able to do that, you should do very well as Kai'Sa against Kassadin.
To learn all of the intricacies of Kai'Sa in order to counter Kassadin during both the early game and mid / late game phases of League of Legends, you should continue reading to learn a few extra lessons on this matchup. If you listen to the build and stats displayed above, you will grow your win rate by a lot and be that much closer to League of Legends pro players.
Kai'Sa most often picks up a similar amount of CS as Kassadin. Champions who on average don't earn many minion kills often don't require much CS to be effective, such as sup champs. These kinds of champions are capable of scaling well off of their abilities and first items alone. Yet, champs with large amounts of CS, such as hyper-carries, usually have to have a lot of items to be effective. In either case, try to exceed the values reported on this page to do well.
The most crucial items to focus on in your Kai'Sa versus Kassadin build consist of Terminus, Kraken Slayer, and Navori Quickblades. When Kai'Sa combined at least these three pieces in her build, she did a lot better when fighting Kassadin than with many other common item sets. In fact, Kai'Sa boasted an average win rate of 46.2% when countering Kassadin with these items in her kit.
To have the best chance of annihilating Kassadin as Kai'Sa, you should take the Hail of Blades, Taste of Blood, Eyeball Collection, Treasure Hunter, Biscuit Delivery, and Magical Footwear runes from the Domination and Inspiration rune sets. Of all the rune combinations that we analyzed for Kai'Sa vs Kassadin counter picks, this sequence of runes yielded the greatest win rate. In fact, these runes gave a 46.2% winrate overall.
If you would like to see Kai'Sa versus Kassadin tips and counter builds for a an individual player tier, feel free to select one from the selection menu displayed above. At first, the stats and guides shown are calculated using all rounds run with these champs.