Garen is only constrained by cooldowns, making items such as Black Cleaver very effective for him.
Garen's regeneration greatly increases if he can avoid receiving damage for several seconds.
Judgment deals maximum damage when only hitting a single target. For effective trading, try to position such that only the enemy champion is hit.
Deny Vayne the opportunity to pin you against walls.
Vayne is fragile - turn the pressure up on her and she will be forced to play cautiously.
The stat comparisons provided here emphasize several strategic Garen against Vayne counter statistics that may help you explain the differences and similarities between the two. As an example, Garen’s KDA ratio ([kills + assists] / deaths) of NaN is greater than Vayne’s ratio of NaN, indicating that Garen may be more central to his team's team fighting effectiveness than Vayne..
Garen often has a slightly smaller longest killing spree than his enemy does. Typically, he receives more damage than Vayne. This commonly reflects differing health capacities; however, it can also show that the one champion has less mobility and thus is unable to flee from additional damage when poked or engaged.
Both LoL champs are great. Both champs have their pros and cons. In League's current meta, Garen usually loses when facing off against Vayne, with a 47.6% win rate. Thus, Garen makes a bad counter for Vayne.
While Garen does have a lower winrate than Vayne, when facing one another, Garen also has a lower level of difficulty that makes him a less complex character to learn and master. You should expect to face a difficult match when picking Garen into Vayne.
Furthermore, Garen also has almost no amount of CC and other utility, a similar amount to Vayne. This makes her just as valuable during teamfights, especially when facing champions with a lot of burst damage.
While there isn't a single best champion overall in League of Legends, in Garen vs Vayne matchups, Vayne is the better champion with a lower win rate, less champion complexity, and a similar amount of utility to help out your allies during teamfights.
Garen is a terribly counter to Vayne. You will do well by focussing your tactics on increasing your gold income and destroying objectives. If you are able to do that, you should do very well as Garen against Vayne.
To truly master Garen in order to counter Vayne during both the early game and mid / late game phases of League of Legends, you should continue reading to pick up a few extra tricks and insights into this matchup. If you mind the build and tips presented here, you should grow your win rate by a lot and be closer to League of Legends pro players.
Garen often accumulates a similar amount of CS relative to Vayne. Champions who on average don't get many minion kills usualy don't need much CS to be valuable teammates, such as sup champs. These kinds of champions are able to scale properly off of their skills, stats, and first items alone. Yet, champions with large amounts of CS, such as hyper-carries, often require a lot of items to be effective. In either situation, try to surpass the numbers shown here to do well.
The most important items to focus on in your Garen versus Vayne build consist of Phantom Dancer, Dead Man's Plate, and Stridebreaker. When Garen incorporated at least these three items in his build, he did much better when facing Vayne than with most other typical item sets. In fact, Garen boasted an average win rate of 47.6% when playing against Vayne with this counter build.
To have the greatest chance of crushing Vayne as Garen, you should equip the Phase Rush, Nimbus Cloak, Celerity, Gathering Storm, Demolish, and Second Wind runes from the Sorcery and Resolve rune sets. Of all the rune builds players used for Garen vs Vayne fights, this combo of runes yielded the highest win rate. In fact, these runes provided a 47.6% win rate overall.
By default, tips, statistics, and builds on how to beat Vayne as Garen are displayed for all skill levels combined. If you want to scope the statistics and builds to a specific skill level, you can use the selection menu located above.