Spider Form is most effective at finishing off enemies with low health; Human Form's Neurotoxin does more damage to healthy foes.
Elise's Spider Form and Spider Form abilities do not cost mana and can be prioritized when you are trying to conserve mana.
When in Spider Form, Spiderlings will attack the target that Elise uses Venomous Bite on.
Zilean is fragile if a team focuses on him, but otherwise he's very difficult to kill. Commit to killing him as a team.
If you're able to match Zilean's speed, it can sometimes be beneficial to wait until his ultimate has faded before landing the killing blow.
The stats shown here clarify some influential Elise against Zilean matchup statistics that can help you grasp the differences between the two. For instance, Elise’s KDA ratio ([kills + assists] / deaths) of NaN is more than Zilean’s KDA ratio of NaN, demonstrating that Elise may be more central to her team's team fighting effectiveness than Zilean. This observation is largely fueled by the difference in kills.
Elise often has a much larger longest killing spree than her foe does. Typically, she takes more damage than Zilean. This typically indicates different amounts of tankyness, yet it can also indicate that the one champ has less agility and thus is not able to escape additional damage when poked or engaged.
Both LoL champs are great champions. Both champs have their pros and cons. In the game's current meta, Elise usually loses when trying to fight Zilean, with a 47.8% win rate. Therefore, Elise makes a poor counter to Zilean.
While Elise does have a lower winrate compared to Zilean, when facing one another, Elise also has a much greater learning curve that makes her a more difficult champion to pick up and master. You may get destroyed when picking Elise into Zileanas her relative depth means that you may not be able to unleash her full potential without a significant amount of practice beforehand.
Furthermore, Elise also has only a small amount of CC and other utility, a similar amount to Zilean. This often makes her just as valuable during team fights, especially when facing champions with a lot of burst damage.
While there is not one best champion for every situation in League of Legends, in Elise vs Zilean matchups, Zilean is the better champ with a lower win rate, more champion depth, and a similar amount of utility to help out your teammates during team fights.
Elise is a terribly counter for Zilean. You will do well by focussing your strategy on maximizing your CS and taking out objectives. If you do that, you should be able to stand on your own as Elise against Zilean.
If you would like to learn all of the intricacies of Elise to counter Zilean during both the early game and mid / late game phases of League of Legends, you should keep reading to gather a few extra tricks and insights into this matchup. If you listen to the build and suggestions presented above, you will increase your win rate significantly and be that much closer to League of Legends pro players.
Elise usually gets less CS relative to Zilean. Champions who on average don't earn many minion kills often don't have to have much CS to be valuable teammates, such as support champions. They are able to scale properly off of their skills, stats, and first items alone. Yet, champions with a lot of CS, such as hyper-carries, often have to have several high cost items to be effective. In either situation, try to do better than the values displayed on this page to do well.
The best items to have in your Elise versus Zilean build consist of Zhonya's Hourglass, Shadowflame, and Stormsurge. When Elise bought at least these three items in her build, she did significantly better when fighting Zilean than with many other typical builds. In fact, Elise boasted an average winrate of 47.8% battling Zilean with these items in her kit.
To have the greatest likelihood of vanquishing Zilean as Elise, you should use the Dark Harvest, Cheap Shot, Eyeball Collection, Relentless Hunter, Coup de Grace, and Triumph runes from the Domination and Precision rune sets. Of all the runes players used for Elise vs Zilean counter picks, this combo of runes yielded the highest win rate. Notably, these runes gave a 47.8% winrate overall.
If you need to view Elise vs Zilean tips and counter builds for a a specific skill level, please choose one from the selection menu above. If viewing for the first time, the stats and build suggestions given are computed using all games finished with both champs.