Spider Form is most effective at finishing off enemies with low health; Human Form's Neurotoxin does more damage to healthy foes.
Elise's Spider Form and Spider Form abilities do not cost mana and can be prioritized when you are trying to conserve mana.
When in Spider Form, Spiderlings will attack the target that Elise uses Venomous Bite on.
Karthus can cast spells for a short duration after he is killed. Move away from his corpse to be safe.
Make sure you always have enough health to survive Requiem, even if you have to go back to the base more frequently to heal.
The stat comparisons shown on this page emphasize some important Elise versus Karthus counter stats that may help you understand the differences between these two champions. As an example, Elise’s KDA ratio ([kills + assists] / deaths) of NaN is more than Karthus’s ratio of NaN, demonstrating that Elise may be more central to her team's team fighting effectiveness than Karthus..
Elise usually has a similar longest killing spree as her foe does. On average, she takes a similar amount of damage to Karthus. This often reflects different amounts of tankyness; however, it can also imply that the one champion has less agility and thus is unable to kite away from further damage when poked or engaged.
Both League champs are great champions. Both have their pros and cons. In the game's current meta, Elise usually wins when playing against Karthus, with a 54.6% win rate. Therefore, Elise makes a great counter for Karthus.
While Elise does have a much higher winrate than Karthus, when they face off with one another, Elise also has a greater level of difficulty that makes her a more challenging character to learn. You should be be fine when picking Elise into Karthusas her relative depth means that you may not be able to reach her full potential without a lot of practice beforehand.
Moreover, Elise also has almost no amount of CC and other utility, a similar amount to Karthus. This often makes her just as valuable during team fights, especially when fighting champions with a ton of burst damage.
While there isn't one best champion for every situation in League of Legends, in Elise vs Karthus matchups, Elise is the better champ with a noticably higher win rate, more champion depth, and a similar amount of utility to help out your allied champions during team fights.
Elise is a great counter for Karthus. You will do well by focussing your play on keeping up your CS and destroying objectives. If you do that, you should hold your own as Elise against Karthus.
To learn all of the intricacies of Elise to counter Karthus during both the lane and mid / late game phases of League of Legends, you should keep reading to learn a few extra tips and tricks for this matchup. If you listen to the build and tips displayed above, you will grow your win rate by a lot and be that much closer to League of Legends pro players.
Elise usually racks up a lot less CS compared to Karthus. Champs who on average don't get much CS usualy don't have to have much CS to be valuable teammates, such as support champions. They are able to scale properly off of their abilities and first items alone. Yet, champs with large amounts of CS, such as hyper-carries, usually require several high cost items to be effective. In either case, try to do better than the numbers reported here to do well.
The most crucial items to prioritize in your Elise versus Karthus build include Zhonya's Hourglass, Shadowflame, and Stormsurge. When Elise bought at least these three pieces in her build, she performed much better when fighting Karthus than with many other common item sets. In fact, Elise had an average winrate of 54.6% when countering Karthus with this counter build.
To have the greatest likelihood of coming out on top against Karthus as Elise, Elise players should use the Electrocute, Cheap Shot, Eyeball Collection, Relentless Hunter, Nimbus Cloak, and Waterwalking runes from the Domination and Sorcery rune sets. Out of all the rune builds that we analyzed for Elise vs Karthus counter picks, this combo of runes resulted in the best win rate. Moreover, these runes averaged a 54.6% winrate overall.
If you want to see Elise versus Karthus tips and counter builds for a a specific player tier, feel free to select one from the selection menu above. By default, the stats and build suggestions given are computed using all rounds played with both champs.