Lead your enemy when targeting with Noxious Blast to ensure the hit.
Use Twin Fang on poisoned stationary targets like monsters and units stunned by her Petrifying Gaze for maximum damage.
Zoe's Paddle Star deals more damage the further it has flown.
Sleepy Trouble Bubble travels further over walls. Stop Zoe from hiding in fog of war to prevent her from setting the spell up.
Zoe must return to her starting point after casting Portal Jump, making her vulnerable to a counterattack.
The stats provided here underscore several important Cassiopeia against Zoe matchup statistics that can help us interpret the differences between this set of champs. Cassiopeia’s KDA ratio ([kills + assists] / deaths) of NaN is greater than Zoe’s KDA ratio of NaN, highlighting that Cassiopeia may be more central to her team's team fighting capability than Zoe..
Cassiopeia normally has a similar longest kill spree as her matchup does. Commonly, she receives more damage than Zoe. This typically indicates differing health capacities; however, it can also hint that the one champion has less mobility and thus is unable to kite away from additional harm when engaged or poked.
Both League champions are great champions. Both champs have their strengths, weaknesses, and counters. In the game's current meta, Cassiopeia usually wins when trying to fight Zoe, with a 51.3% win rate. Thus, Cassiopeia makes a good counter for Zoe.
While Cassiopeia does have a higher winrate than Zoe, when facing one another, Cassiopeia also has a much greater difficulty level that makes her a more complex character to pick up and master. You should be careful when picking Cassiopeia into Zoeas her relative depth means you may not be able to unleash her full potential without a lot of practice beforehand.
Moreover, Cassiopeia also has a good amount of CC and other utility, a similar amount to Zoe. This makes her just as valuable during team fights, especially when facing champions with a ton of burst damage.
While there isn't one best champion for every situation in League of Legends, in Cassiopeia vs Zoe matchups, Cassiopeia is the better champ with a higher win rate, more champion depth, and a similar amount of utility to help out your teammates during team fights.
Cassiopeia is a decent counter to Zoe. Focus your strategy on increasing your CS and destroying objectives. If you are able to do that, you should be able to stand on your own as Cassiopeia against Zoe.
To truly master Cassiopeia in order to counter Zoe during both the laning and mid / late game phases of League of Legends, you should keep reading to pick up a few extra lessons on this matchup. If you listen to the build and tips displayed here, you should increase your win rate by a lot and be that much closer to League of Legends pro players.
Cassiopeia often picks up a similar amount of CS as Zoe. Champs who typically don't earn many minion kills typically don't need much CS to be effective, such as supports. They are able to scale properly off of their skills, stats, and first items alone. Yet, champions with a lot of CS, such as hyper-carries, usually need a lot of items to be effective. In either case, try to exceed the numbers reported on this page to do well.
The top items to focus on in your Cassiopeia versus Zoe build include Seraph's Embrace, Liandry's Torment, and Rod of Ages. When Cassiopeia bought at least these three items in her build, she performed significantly better countering Zoe than with many other typical counter builds. In fact, Cassiopeia had an average winrate of 51.3% when countering Zoe with these items in her kit.
To have the greatest probability of crushing Zoe as Cassiopeia, Cassiopeia players should use the Conqueror, Presence of Mind, Legend: Tenacity, Last Stand, Manaflow Band, and Transcendence runes from the Precision and Sorcery rune sets. Of all the rune builds players chose for Cassiopeia vs Zoe matchups, this order of runes yielded the highest win rate. Moreover, these runes gave a 51.3% win rate overall.
If you want to view Cassiopeia x Zoe tips and counter builds for a a particular rank, feel free to choose one from the selection menu shown above. At first, the statistics and guides shown are calculated using all matches run with both champions.