Lead your enemy when targeting with Noxious Blast to ensure the hit.
Use Twin Fang on poisoned stationary targets like monsters and units stunned by her Petrifying Gaze for maximum damage.
Ryze is especially dangerous to opponents that are marked with Flux.
Use Realm Warp's windup time to figure out how to deal with what may be coming out of the portal.
Crowd controlling Ryze during Realm Warp's windup will cancel the portal.
The stat comparisons provided here show some vital Cassiopeia versus Ryze counter stats that may help you realize the differences between the pair. For instance, Cassiopeia’s KDA ratio ([kills + assists] / deaths) of NaN is better than Ryze’s KDA ratio of NaN, highlighting that Cassiopeia may be more central to her team's team fighting capability than Ryze..
Cassiopeia usually has a slightly larger longest kill spree than her matchup does. Typically, she receives a similar amount of damage to Ryze. This is usually reflective of different amounts of tankyness; however, it can also show that the champ with higher HP has less agility and thus is not able to flee from further harm when poked or engaged.
Both League champs are great champions. Both champs have their strengths, weaknesses, and counters. In the game's current meta, Cassiopeia usually wins when facing off against Ryze, with a 51.3% win rate. Therefore, Cassiopeia makes a good counter to Ryze.
While Cassiopeia does have a higher winrate compared to Ryze, when they face off with one another, Cassiopeia also has a much greater difficulty level that makes her a more difficult champion to pick up and master. You still need to be cautious when picking Cassiopeia into Ryzeas her relative depth means that you may not be able to unleash her full potential without a significant amount of practice beforehand.
Moreover, Cassiopeia also has a good amount of utility and CC, a similar amount to Ryze. This makes her just as valuable during teamfights, especially when facing champions with a ton of burst damage.
While there isn't one best champion for every situation in League of Legends, in Cassiopeia vs Ryze matchups, Cassiopeia is the better champ with a higher win rate, more champion depth, and a similar amount of utility to help out your allies during teamfights.
Cassiopeia is a decent counter to Ryze. Focus your gameplay on increasing your CS and taking out objectives. If you are able to do that, you should hold your own as Cassiopeia against Ryze.
To truly master Cassiopeia in order to counter Ryze during both the laning and mid / late game phases of League of Legends, you should keep reading to learn a few extra tricks and insights into this matchup. If you pay attention to the build and stats shown here, you should increase your win rate significantly and be closer to League of Legends pro players.
Cassiopeia most often picks up a similar amount of CS compared to Ryze. Champs who on average don't earn many minion kills typically don't have to have much CS to be effective, such as supports. These kinds of champions are able to scale well off of their abilities and first items alone. Yet, champions with a lot of CS, such as hyper-carries, usually need several high cost items to be effective. In either situation, try to do better than the numbers shown here to do well.
The most crucial items to focus on in your Cassiopeia versus Ryze build consist of Seraph's Embrace, Rylai's Crystal Scepter, and Rod of Ages. When Cassiopeia included at least these three pieces in her build, she performed much better when facing Ryze than with many other commonly used counter builds. In fact, Cassiopeia had an average winrate of 51.3% when countering Ryze with these items in her kit.
To have the greatest likelihood of annihilating Ryze as Cassiopeia, Cassiopeia players should use the Conqueror, Presence of Mind, Legend: Tenacity, Last Stand, Manaflow Band, and Transcendence runes from the Precision and Sorcery rune sets. Of all the runes that we analyzed for Cassiopeia vs Ryze matchups, this combo of runes resulted in the greatest win rate. Moreover, these runes provided a 51.3% winrate overall.
By default, tips, statistics, and builds on how to beat Ryze as Cassiopeia are displayed for all ranked divisions. If you would like to scope the stats and builds to a particular skill level, you should use the selection menu located earlier in the counter matchup guide.