Fire 90 Caliber Net away from the opponent to close the gap or hop over walls.
Avoid using Ace in the Hole in large team melees as it might be blocked by the wrong target.
Make use of her Yordle Snap Traps by placing them pre-emptively to ensure that you'll have one off of cooldown during combat.
Deny Vayne the opportunity to pin you against walls.
Vayne is fragile - turn the pressure up on her and she will be forced to play cautiously.
The stats shown here underscore some critical Caitlyn vs. Vayne matchup stats that can help us appreciate the differences and similarities between the two. As an example, Caitlyn’s KDA ratio ([kills + assists] / deaths) of NaN is better than Vayne’s KDA ratio of NaN, demonstrating that Caitlyn may be more central to her team's team fighting capacity than Vayne..
Caitlyn typically has a similar longest kill spree as her counter does. Commonly, she receives a similar amount of damage to Vayne. This commonly reflects differing health capacities; however, it can also illustrate that the one champion has less mobility and thus is not able to kite away from additional damage when engaged or poked.
Both League champs are great champions. Both have their pros and cons. In League's current meta, Caitlyn usually fairs equally well when facing off against Vayne, with a 49.6% win rate. Therefore, Caitlyn makes an ok counter to Vayne.
While Caitlyn does have a lower win rate than Vayne, when they face off with one another, Caitlyn also has a lower difficulty level that makes her a less time consuming character to learn and master. You still need to be cautious when picking Caitlyn into Vayne.
Moreover, Caitlyn also has only a small amount of CC and other utility, a similar amount to Vayne. This makes her just as valuable during teamfights, especially when fighting champions with a lot of burst damage.
While there isn't a single best champion overall in League of Legends, in Caitlyn vs Vayne matchups, Vayne is the better champion with a similar win rate, less champion complexity, and a similar amount of utility to help out your allies during teamfights.
Caitlyn is a somewhat poor counter for Vayne. You will do well by focussing your actions on increasing your gold and cs and clearing objectives. If you are able to do that, you should hold your own as Caitlyn against Vayne.
To truly master Caitlyn in order to counter Vayne during both the early game and mid / late game phases of League of Legends, you should keep reading to learn a few extra tricks and insights into this matchup. If you mind the build and suggestions displayed here, you will grow your win rate significantly and be that much closer to League of Legends pro players.
Caitlyn most often accumulates a similar amount of CS relative to Vayne. Champions who typically don't acquire much CS usualy don't require much CS to be effective, such as sup champs. These kinds of champions are capable of scaling well off of their abilities and first items alone. Yet, champs with a lot of CS, such as hyper-carries, typically have to have a lot of items to be effective. In either case, try to exceed the values shown on this page to do well.
The ideal items to prioritize in your Caitlyn versus Vayne build consist of Lord Dominik's Regards, Youmuu's Ghostblade, and Axiom Arc. When Caitlyn bought at least these three pieces in her build, she did significantly better vs Vayne than with many other typical counter builds. In fact, Caitlyn boasted an average win rate of 49.6% battling Vayne with these items in her kit.
To have the greatest chance of coming out on top against Vayne as Caitlyn, you should take the Fleet Footwork, Overheal, Legend: Bloodline, Coup de Grace, Absolute Focus, and Gathering Storm runes from the Precision and Sorcery rune sets. Of all the rune sets players chose for Caitlyn vs Vayne LoL games, this mix of runes resulted in the greatest win rate. Notably, these runes averaged a 49.6% winrate overall.
If you would like to view Caitlyn vs Vayne tips and builds for a an individual division, please choose one from the selection menu provided above. At first, the statistics and build suggestions displayed are computed using every round completed with these champs.