Molten Shield is a good spell to cast to work up to Annie's stun, so sometimes it's beneficial to grab at least 1 rank in it early.
Striking killing blows on minions with Disintegrate enables Annie to farm extremely well early in the game.
Storing a stun for use with her ultimate can turn the tide of a team fight.
Spell Shields won't block the damage from Deadly Venom, but they will block the effects Twitch can trigger with it.
If you suspect Twitch has left the lane, let your teammates know that Twitch is ''MIA.''
Twitch is fragile. Work with teammates to focus on him when you're able to catch him out of Camouflage.
The stat comparisons shown on this page clarify several influential Annie vs. Twitch matchup statistics that can help us grasp the differences and similarities between the pair. Annie’s KDA ratio ([kills + assists] / deaths) of NaN is better than Twitch’s ratio of NaN, indicating that Annie may be more central to her team's team fighting potential than Twitch..
Annie typically has a slightly smaller longest kill spree than her matchup does. Commonly, she takes less damage than Twitch. This typically indicates different amounts of tankyness, but it can also imply that the one champ has less agility and thus is not able to kite away from additional damage when poked or engaged.
Both LoL champions are great. Both champs have their strengths, weaknesses, and counters. In the game's current meta, Annie usually loses when taking on Twitch, with a 48.9% win rate. Therefore, Annie makes a poor counter for Twitch.
While Annie does have a lower win rate than Twitch, when on opposite teams, Annie also has a greater learning curve that makes her a more complex character to learn. You still need to be cautious when picking Annie into Twitch.
Additionally, Annie has a good amount of utility and CC, a similar amount to Twitch. This makes her just as valuable during team fights, especially when fighting champions with a ton of burst damage.
While there isn't a single best champion for every situation in League of Legends, in Annie vs Twitch matchups, Twitch is the better champ with a lower win rate, similar champion depth, and a similar amount of utility to help out your team members during team fights.
Annie is a somewhat poor counter for Twitch. You will do well by focussing your actions on keeping up your gold income and taking out objectives. If you do that, you should do very well as Annie against Twitch.
If you would like to truly master Annie in order to counter Twitch during both the laning and mid / late game phases of League of Legends, you should keep reading to learn a few extra lessons on this matchup. If you pay attention to the build and stats displayed above, you will increase your win rate by a lot and be that much closer to League of Legends pro players.
Annie on average racks up a similar amount of CS as Twitch. Champs who typically don't acquire much CS usualy don't have to have much CS to be effective, such as support champions. They are capable of scaling well off of their skills, stats, and first items alone. Yet, champs with large amounts of CS, such as hyper-carries, often have to have several high cost items to be effective. In either case, try to surpass the numbers shown on this page to do well.
The most important items to focus on in your Annie versus Twitch build include Malignance, Shadowflame, and Liandry's Torment. When Annie bought at least these three pieces in her build, she performed much better countering Twitch than with many other typical builds. In fact, Annie had an average win rate of 48.9% when playing against Twitch with this counter build.
To have the greatest probability of vanquishing Twitch as Annie, you should use the Electrocute, Cheap Shot, Eyeball Collection, Relentless Hunter, Manaflow Band, and Absolute Focus runes from the Domination and Sorcery rune sets. Of all the rune builds players used for Annie vs Twitch clashes, this combination of runes yielded the best win rate. Notably, these runes averaged a 48.9% winrate overall.
By default, tips, statistics, and builds on how to beat Twitch as Annie are displayed for all ranked divisions combined. If you would like to filter the stats and builds to a particular player tier, you should use the selection menu located earlier in the counter matchup guide.