Molten Shield is a good spell to cast to work up to Annie's stun, so sometimes it's beneficial to grab at least 1 rank in it early.
Striking killing blows on minions with Disintegrate enables Annie to farm extremely well early in the game.
Storing a stun for use with her ultimate can turn the tide of a team fight.
Get boots early when playing against Syndra, they'll help you avoid many of her spells.
Attack Syndra after she's used Scatter the Weak, it has a long cooldown so she'll be vulnerable.
At max rank Syndra's spells gain bonus effects and change in appearance.
The stats provided here clarify some significant Annie versus Syndra matchup statistics that may help us understand the distinctions between the two. Annie’s KDA ratio ([kills + assists] / deaths) of NaN is more than Syndra’s KDA ratio of NaN, highlighting that Annie may be more central to her team's team fighting effectiveness than Syndra..
Annie often has a similar longest kill spree as her enemy does. Typically, she receives a similar amount of damage to Syndra. This commonly reflects different amounts of tankyness, yet it can also imply that the champion with higher HP has less agility and thus is unable to escape further damage when poked or engaged.
Both League champions are great champions. Both have their strengths, weaknesses, and counters. In the game's current meta, Annie usually wins when playing against Syndra, with a 51.7% win rate. As a result, Annie makes a good counter to Syndra.
While Annie does have a higher winrate than Syndra, when facing one another, Annie also has a lower learning curve that makes her a less difficult champion to pick up and master. You should be careful when picking Annie into Syndra.
Moreover, Annie also has a good amount of CC and other utility, a similar amount to Syndra. This often makes her just as valuable during team fights, especially when fighting champions with a lot of burst damage.
While there is not a single best champion overall in League of Legends, in Annie vs Syndra matchups, Annie is the better champ with a higher win rate, less champion complexity, and a similar amount of utility to help out your allied champions during late stage team fights.
Annie is a decent counter for Syndra. You will do well by focussing your strategy on maximizing your gold and cs and clearing objectives. If you are able to do that, you should be able to stand on your own as Annie against Syndra.
To truly master Annie to counter Syndra during both the lane and mid / late game phases of League of Legends, you should continue reading to pick up a few extra tricks and insights into this matchup. If you listen to the build and tips displayed above, you should increase your win rate significantly and be closer to League of Legends pro players.
Annie most often accumulates a similar amount of CS relative to Syndra. Champions who typically don't acquire many minion kills typically don't require much CS to be valuable teammates, such as support champions. These kinds of champions are able to scale well off of their skills, stats, and first items alone. Yet, champs with a lot of CS, such as hyper-carries, often need many items to be effective. In either situation, try to surpass the values displayed on this page to do well.
The most important items to prioritize in your Annie versus Syndra build include Shadowflame, Stormsurge, and Luden's Companion. When Annie included at least these three items in her build, she performed a lot better when facing Syndra than with many other typical item sets. In fact, Annie boasted an average win rate of 51.7% when playing against Syndra with these items in her kit.
To have the greatest chance of defeating Syndra as Annie, you should use the Electrocute, Cheap Shot, Eyeball Collection, Relentless Hunter, Absolute Focus, and Manaflow Band runes from the Domination and Sorcery rune sets. Out of all the runes players used for Annie vs Syndra counterpicks, this combination of runes resulted in the best win rate. Notably, these runes averaged a 51.7% winrate overall.
If you would like to see Annie vs Syndra tips and counter stats for a a specific division, feel free to choose one from the selection menu shown above. By default, the stats and guides displayed are calculated using all rounds finished with these champions.