Molten Shield is a good spell to cast to work up to Annie's stun, so sometimes it's beneficial to grab at least 1 rank in it early.
Striking killing blows on minions with Disintegrate enables Annie to farm extremely well early in the game.
Storing a stun for use with her ultimate can turn the tide of a team fight.
Karthus can cast spells for a short duration after he is killed. Move away from his corpse to be safe.
Make sure you always have enough health to survive Requiem, even if you have to go back to the base more frequently to heal.
The stats shown on this page clarify some important Annie vs. Karthus matchup statistics that may help you distinguish the differences between this set of champions. As an example, Annie’s KDA ratio ([kills + assists] / deaths) of NaN is better than Karthus’s ratio of NaN, highlighting that Annie may be more central to her team's team fighting capacity than Karthus..
Annie normally has a similar longest kill spree as her counter does. Commonly, she takes less damage than Karthus. This commonly reflects differing health capacities, but it can also hint that the one champion has less agility and thus is not able to escape additional harm when engaged or poked.
Both LoL champs are great. Both champs have their pros and cons. In the game's current meta, Annie usually wins when playing against Karthus, with a 52.1% win rate. As a result, Annie makes a good counter for Karthus.
While Annie does have a higher win rate compared to Karthus, when on opposite teams, Annie also has a lower learning curve that makes her a less time consuming champion to learn and master. You should be be fine when picking Annie into Karthus.
Additionally, Annie has a good amount of CC and other utility, a similar amount to Karthus. This makes her just as valuable during team fights, especially when facing champions with a ton of burst damage.
While there is not a single best champion overall in League of Legends, in Annie vs Karthus matchups, Annie is the better champ with a noticably higher win rate, less champion complexity, and a similar amount of utility to help out your teammates during team fights.
Annie is an above average counter for Karthus. You will do well by focussing your actions on keeping up your CS and destroying objectives. If you can do that, you should do very well as Annie against Karthus.
If you would like to truly master Annie to counter Karthus during both the lane and mid / late game phases of League of Legends, you should keep reading to learn a few extra lessons on this matchup. If you pay attention to the build and tips presented here, you will increase your win rate significantly and be closer to League of Legends pro players.
Annie typically picks up more CS compared to Karthus. Champions who typically don't acquire many minion kills usualy don't require much CS to be effective, such as support champions. These kinds of champions are capable of scaling properly off of their abilities and first items alone. Yet, champions with a lot of CS, such as hyper-carries, typically need several high cost items to be effective. In either case, try to do better than the values shown here to do well.
The top items to focus on in your Annie versus Karthus build include Malignance, Shadowflame, and Stormsurge. When Annie incorporated at least these three items in her build, she did a lot better vs Karthus than with many other common counter builds. In fact, Annie had an average win rate of 52.1% when playing against Karthus with these items in her kit.
To have the highest probability of crushing Karthus as Annie, you should use the Electrocute, Cheap Shot, Eyeball Collection, Relentless Hunter, Absolute Focus, and Manaflow Band runes from the Domination and Sorcery rune sets. Of all the runes we have analyed for Annie vs Karthus counterpicks, this set of runes resulted in the greatest win rate. Notably, these runes gave a 52.1% win rate overall.
By default, tips, statistics, and builds on how to beat Karthus as Annie are given for all skill levels, merged. If you want to narrow the statistics and builds to a specific rank, you may use the selection menu located at the top of this page.