Since Syndra's abilities are AOE, it's hard to harass the enemy in lane without pushing the minion wave to the enemy turret. This is not advisable as the minion equilibrium won't be in your favor.
Maximize the damage from Unleashed Power by using it when there are many spheres on the map. It has a low cooldown so feel free to use it liberally.
League of Legends Syndra players will likely find her to be a challenging character to build out properly. You'll find that her build varies when she is playing against either generic or specialized team comps, meaning you shouldn't follow the same Syndra build every game of League of Legends
The best items to incorporate into your champion's build are: Luden's Tempest, Seraph's Embrace, and Rabadon's Deathcap. Players who included these items in their gear had a greater winrate than players who utilized other builds for Syndra. Similarly, if you are battling a varied enemy team comp, you should really consider grabbing Syndra the Sorcery, and Resolve runes. In recent matches, she won the largest percentage of her matches when using these runes.
We calculated our Syndra build guidance by analyzing 70,514 recently ranked League rounds with her selected. We only recommend the best winrate Syndra builds that have been used by ranked players enough times for us to propose them. With so many matches in our dataset, we are quite confident in our recommended builds.