Kassadin needs to be careful during the laning phase because he has little mobility early on and can only get last hits in melee range.
Make sure the enemy team is focused on your allies before entering a teamfight, never be the one to initiate or be in the front lines.
League of Legends Kassadin players will likely find him to be a dynamic character to build out properly. You'll notice that his build is modified when he is playing against either diversified or homogenous team comps, indicating you should not follow the same Kassadin build every game of League of Legends
The most important items to incorporate into your champ's build include: Crown of the Shattered Queen, Seraph's Embrace, and Lich Bane. Those who added these items in their builds had a much higher winrate than those who used other Kassadin builds. Likewise, if you are battling a mixed enemy team arrangement, you should really consider grabbing yourself the Inspiration, and Domination runes. In recent games, he won the largest percentage of his matches when built with these runes.
We set our Kassadin build suggestions by analyzing 46,074 recently ranked League rounds with him in them. We only advise the top winrate Kassadin builds that were used by ranked players enough times for us to reccomend them. With so many matches in our data, we are very confident in our recommended builds.